Archive for the ‘Vit. D and Gait Control-Neurology May 2011’ Category

Vit. D and Gait Control-Neurology May 2011

May 11, 2011

Neurology. 2011 May 10;76(19):1617-22. Epub 2011 Apr 6.

Biology of gait control: Vitamin D involvement-Beauchet O, Annweiler C, Verghese J, Fantino B, Herrmann FR, Allali G.

Department of Internal Medicine and Geriatrics, Angers University Hospitals, 49933 Angers cedex 9, France

Pub Med.Gov:  http://www.ncbi.nlm.nih.gov/pubmed/21471466

side note…many Vit. D related articles below

CONCLUSIONS:

Low serum 25OHD concentrations were associated with high STV reflecting a disturbed gait control. This association could be explained by a possible action of vitamin D on different components involved in gait control.

Abstract

BACKGROUND:

Adverse neuromuscular events have been described in case of low serum 25-hydroxyvitamin D (25OHD) concentrations, suggesting that vitamin D may be involved in gait stability. The objective of this cross-sectional study was to examine the association between stride-to-stride variability of stride time (STV) and serum 25OHD concentration in adults aged 65 years and older.

 METHODS:

STV and 25OHD concentration were assessed in 411 community-dwelling older adults (mean age 70.4 ± 1.8 years, 57.9% women). The following established 25OHD thresholds were used: severe 25OHD insufficiency <10 ng/mL, moderate 10-30 ng/mL, and normal >30 ng/mL. Age, number of drugs used per day, use of psychoactive drugs, depressive symptoms, cognitive decline, history of falls, distance visual acuity, lower limb proprioception, center of mass (CoM) motion, and walking speed were considered as potential confounders.

RESULTS:

A total of 16.6% (n = 68) of subjects had severe 25OHD insufficiency, 70.3% (n = 289) moderate insufficiency, and 13.1% (n = 54) normal concentrations. In the full adjusted and the stepwise backward linear regression models, high STV (worse performance) was associated with severe 25OHD insufficiency (p = 0.028 and p = 0.044, respectively), high CoM motion (p = 0.031 and p = 0.014, respectively), and low lower limb proprioception score (p = 0.017 and p = 0.008, respectively). The stepwise backward regression model also showed that high STV was associated with female gender (p = 0.041).

Vit D for Higher Levels of Health 2012

Vit D for Cancer Prevention-Annals of Epidemiology 2009

Vit D- Reduction in breast cancer risk-Cancer Causes Ctrl 2010

Vit D2 versus D3-Meta Analysis-John J. Cannell, M.D.

Vit D3 and the Flu-Epidemiology and Infection-2007

Vit. D- The Food and Nutrition Board has failed millions

Vit. D-What We Have Learned About Vitamin D Dosing

Vitamin D Supplementation: An Update-U.S. Pharmacist 11/11/2010

Vitamin D3 Helps Clear Amyloid in Alzheimer’s Disease

Vit. D3-promote fat loss and gain good muscle in women

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